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Although the Index Patient defined in the 2003 Guideline was aged 50 or older, the Panel has lowered the age for inclusion in this Guideline, as this lower age group can present with LUTS.

LUTS include storage and/or voiding disturbances common in aging men.

Thus, this disease entity is particularly complex to evaluate, survey and treat.

In men, enlargement of the prostate gland from hyperplasia can cause BOO and be a major cause of LUTS or mimicked by other issues, such as infection, malignancy, central-peripheral neurologic disease or overactivity/hypoactivity of detrusor muscles.

Wei, MD The exact etiology is unknown; however, the similarity between BPH and the embryonic morphogenesis of the prostate has led to the hypothesis that BPH may result from a "reawakening" in adulthood of embryonic induction processes.

These were also important considerations when assessing BPH and deciding when treatment is indicated.

La ligne 1 du réseau Cabus, Beausoleil-Palatinat-Hôpital, dessert le Centre Hospitaliser Spécialisé de Sarreguemines, en correspondance avec les lignes 2 et 3 au centre-ville (arrêts Eden et Utzschneider).

Pour vous rendre au CHS vous pourrez emprunter cette ligne de Bus, et vous arrêter à l’arrêt « Hôpital ».

Detrusor overactivity is thought to be a contributor to the storage symptoms seen in LUTS.

Benign prostatic hyperplasia (BPH) is a histologic diagnosis that refers to the proliferation of smooth muscle and epithelial cells within the prostatic transition zone. The presence of moderate-to-severe LUTS was also associated with the development of acute urinary retention (AUR) as a symptom of BPH progression, increasing from a prevalence of 6.8 episodes per 1000 patient years of follow-up in the overall population to a high of 34.7 episodes in men aged 70 and older with moderate to severe LUTS.

This guideline discusses proper evaluation and management, including interventional therapy, and treatment alternatives. Another study has estimated that 90% of men between 45 and 80 years of age suffer some type of LUTS.

This 2010 Guideline reviews a number of important aspects in the management of LUTS presumed secondary to BPH including available diagnostic tests to identify the underlying pathophysiology and to assist in symptom management.

Pharmacotherapies-- including complementary and alternative medications (CAM) and watchful waiting, as well as lifestyle issues-- are addressed.

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